This study was concerned with chromium as a potential carcinogenic contaminant in 64 wells located in five aquifers, southwest of Iran. A probabilistic health risk assessment indicated a high risk to the local residents including adults and children in the study area. A sequential sensitivity analysis and a novel approach known as multivariate global sensitivity analysis using both principal component analysis and B-spline were applied to investigate the behavior of health risk model along time considering four independent input parameters in the risk equation. In this context, based on the results of sensitivity analysis, concentration of chromium in drinking water (Cw) and body weight (W) were the most influential parameters. Random forest (RF) was used as a variable selection method to choose the most influential parameters for the prediction of chromium. Five parameters, among 13 water quality variables, including phosphate, nitrate, fluoride, manganese and iron were selected by RF as the most important parameters for spatial prediction. Hybrid methods of RF and ordinary kriging (RFOK) and RF and inverse distance weighting (RFIDW) were then applied for spatial prediction of Cr using the secondary variables. The RFOK and RFIDW were more efficient than that of ordinary kriging (OK) with respect to a cross-validation algorithm. For instance, in terms of relative root mean squared error, the performance of OK was improved from 31.72 to 23.21 and 23.61 for RFOK and RFIDW, respectively.
A field study was conducted in an iron mine in Hamedan (Iran) to find native accumulator plants and to evaluate the extent of metal bioaccumulation in the naturally growing vegetation. The concentrations of total As, Cd, Cr, Fe, Mn, Mo, Ni, Pb, Si, and Zn were found to be higher in the mine than in soil. These plants accumulated the highest amounts of the following metals in their roots: Euphorbia cheiradenia As, Stipa barbata Cd, Pb and Cr, Euphorbia macroclada Cu, Centaurea iberica Fe, Reseda lutea Mo, Salvia spinosa Ni and Zn, and Xanthium strumarium Se. In the aerial parts, the highest metal accumulation was found in Epilobium fragilis As, Carthamus oxyacantha Cd, Fe, Mn, and Pb, Verbascum speciosum Cu, Centaurea iberica Mo, Salvia spinosa Ni and Cr, Glaucium grandiflorum Se, and Malva neglecta Zn. Enrichment factors and bioconcentration factors were also determined; C. oxyacantha, S. spinosa, M. neglecta, C. iberica, V. speciosum, G. grandiflorum, and E. fragilis are the most effective accumulators and are proposed for phytoremediation of polluted soils. 相似文献
Depleted uranium (DU) is widely used in military anti-armor weapons. Recent evidence suggested that oxidative stress and mitochondrial dysfunction may contribute to DU-induced toxicity. However, the underlying mechanisms of DU toxicity in mitochondria are not well understood. In this study, liver mitochondria were obtained from Wistar rats treated with DU in the form of uranyl acetate (UA) (0.5, 1 or 2 mg/kg i.p.) using differential centrifugation. For in vitro experiments, control rat liver mitochondria were incubated with different concentrations of UA (50, 100 or 200 μM) for 1 hr. Mitochondrial reactive oxygen species (ROS) production, collapse of mitochondrial membrane potential, and mitochondrial swelling were examined by flow cytometry. Mitochondrial sources of ROS formation were determined using specific substrates and inhibitors. Extent of lipid peroxidation (LPO) and glutathione (GSH) oxidation, and also complex II and IV activities were detected via spectroscopy. Further, the concentration of ATP and ATP/ADP ratio was measured using luciferase enzyme and release of cytochrome c from mitochondria which was detected by ELISA kit. UA induced succinate-supported mitochondrial ROS production, elevated LPO levels, GSH oxidation, and mitochondrial complex II inhibition. UA also induced mitochondrial permeability transition and increase in cytochrome c release which subsequently disturbed oxidative phosphorylation and reduced the mitochondrial ATP concentration. Data suggest that mitochondrial oxidative stress and uncoupling of oxidative phosphorylation may play key roles in DU-induced hepatic toxicity. 相似文献
Frontline healthcare workers (HCWs) looking after COVID-19 patients are at high risk of developing mental health problems. Both preventive and interventional initiatives are essential, therefore, to maintain and improve the mental health of HCWs and ultimately to enhance the quality of care that they provide. This qualitative content analysis study, conducted in Iran between September 2020 and February 2021, involved the gathering of data on the issue through face-to-face interviews with 22 HCWs working directly with COVID-19 patients. Data analysis led to the generation of 163 codes, 45 categories (16 risk factors and 29 consequences), and 9 themes. Overall, the results suggest that caring for a patient with COVID-19 is associated with positive and negative psychological impacts. Measures such as increasing sensitivity to crisis situations, self-adjustment skills training, and identifying signs of job burnout owing to moral conflicts can reduce or eliminate the risk of negative psychological consequences among HCWs. 相似文献
Journal of Material Cycles and Waste Management - In this study, a hybrid of support vector regression and a modified tunicate swarm algorithm (SVR-MTSA) strategy is developed to optimize the... 相似文献
Environment, Development and Sustainability - This study is an attempt to develop ecotourism in Nehbandan County, in the South Khorasan Province, Iran, by representing unknown areas that have... 相似文献
The present study aims to develop the Theory of Planned Behavior (TPB) to explain comprehensively the establishment of intention and behavior toward source separation of waste. The extended TPB involves the significant structures affecting the behavior along with the original variables of TPB model. Data were gathered from 420 students in Ferdowsi University, Iran, using questionnaires, and analyzed by cluster analysis, discriminant analysis and structural equation modelling techniques (SEM). The cluster analysis identified three distinct grouping according to TPB constructs, and it was validated by discriminant analysis. SEM results displays that motivation had the most important impact on intention, followed by moral obligation, perceived behavior control, subjective norm, situational factor and attitude. Fit statistic of the extended TPB model was good and had better explanatory power compared to the original TPB. It describes 81 and 57% of the variance for intention and behavior toward source separation waste, respectively. 相似文献
The present research introduces a well to wire pseudo comprehensive carbon footprint model for combined cycle power plants. The mentioned model integrates land use change model, operational model and transmission and distribution model into one comprehensive model. The parameters which their effects are considered in the integrated model are: fuel type, fuel transmission type, emission for fuel extraction and processing, own consumption of the plant, degradation, site ambient condition, transmission and distribution losses. For quantifying the effectiveness of each parameter, sensitivity analyses based on different life cycle scenarios are performed. The result shows that the effect of land use change is negligible. The carbon footprint of electrical energy produced in combined cycle plant until it is delivered to the end users varies from 321 to 522 g CO2 eq/kWh. 相似文献
Due to the important role that the application of mathematical programming models have in determining optimal cropping patterns, this research presents a sustainable cropping pattern that considers selected economic, environmental, and social goals together. Using a random sampling method, a sample size of 168 farmers was selected in the Sari County, Iran. Our results showed that economic, self-sufficiency, environmental, and social goals have a distinctly different impact on cropping pattern performance. Compared to the current cropping pattern, the gross margins for economic and social goals increased by nearly 11 and 2 %, respectively, and the gross margins for self-sufficiency and environmental goals decreased by nearly 2 and 36 %. Interestingly, it has been found that the performance of the current cropping pattern has an average positive impact of 6 % if economic, self-sufficiency, environmental, and social (employment) goals are realized simultaneously. 相似文献